Paget's Awareness Day 2021

The Treatment Story - The Past, Present and Future Treatment of Paget's Disease of Bone

Each episode explores a different aspect of treatment. Leading experts explore how bisphosphonates were developed, how they work and the significance of current and future research. We also interview patients about their experiences.

Paget's Awareness Day 2021 - The Treatment Story - Introduction

An introduction to The Treatment Story series created for Paget's Awareness Day 2021, from our Chair, Professor Stuart Ralston.

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The Treatment Story - Episode 1

The discovery of bisphosphonates for Paget's disease -
Prof Stuart Ralston, Chair of the Paget's Association, interviews the Honorary President, Prof Graham Russell, …

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The Treatment Story - Episode 2

The early years of bisphosphonate treatment -
Prof Stuart Ralston interviews Dr Roger Smith. Prof Graham Russell collaborated with Dr Smith, in Oxford, to perform the first hum…

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The Treatment Story - Episode 3

Studying things that matter to patients​ -
Prof Stuart Ralston interviews Prof Ian Reid, from the University of Auckland, New Zealand, who discusses important clinical trials. …

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The Treatment Story - Episode 4

The mechanism of action of bisphosphonates in Paget’s -
Why do some people have a flu-like reaction to certain bisphosphonates? How do different bisphosphonates work? Prof Rals…

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The Treatment Story - Episode 5

What Paget's disease is and the effects of treatment -
How does Paget’s disease affect the bone’s normal repair and renewal process (remodelling)? What effect do bisphosph…

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The Treatment Story - Episode 6

Linda’s experience of treatment for Paget’s disease -
An infusion of zoledronic acid helped Linda Fenlon but how long did it last and what else did she try? Prof Stuart Ralston…

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The Treatment Story - Episode 7

Current and future research into Paget's disease -
What is the relationship between bone turnover and symptoms? What does it mean for those affected by Paget’s disease? Pr…

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The Treatment Story - Episode 8

A patient's experience of Paget's disease -
Mr Keith Simpson discusses his experience of pain, treatment and surgery, in relation to Paget's disease, as he is in…

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